- Cabrera, Jolbert
- Cabrera, Jose
- Cabrera, Miguel
- Cabrera, Orlando
- Caffey, Jason
- Cairns, Eric
- Cairo, Miguel
- Calabria, John
- Calcavecchia, Mark
- Calder, Kyle
- Caldwell, Mike
- Calhoun, Jim
- Camby, Marcus
- Cameron, Cam
- Cameron, Mike
- Campanella, Roy
- Campbell, Brian
- Campbell, Chad
- Campbell, Chris
- Campbell, Dan
- Campbell, Earl
- Campbell, Elden
- Campbell, Jim
- Campbell, Joe
- Campbell, Mark
- Campbell, Stephen
- Campoli, Chris
- Canidate, Trung
- Canizares, Jose Maria
- Cannon, Joe
- Canseco, Jose
- Canty, Chris
- Caporale, Mike
- Capriati, Jennifer
- Capuano, Jack
- Cardinal, Brian
- Carew, Rod
- Carey, Max
- Carlton, Steve
- Carney, Keith
- Caron, Sebastien
- Carpenter, Chris
- Carpenter, Keion
- Carr, Calen
- Carr, Chris
- Carr, William
- Carrara, Giovanni
- Carrasco, Hector
- Carroll, Dennis
- Carswell, Dwayne
- Carter, Anson
- Carter, Anthony
- Carter, Chris
- Carter, Cris
- Carter, Dale
- Carter, Dwight
- Carter, Jim
- Carter, Jonathan
- Carter, Kevin
- Carter, Marty
- Carter, Tim
- Carter, Tom
- Carter, Tony
- Carter, Tyrone
- Carter, Vince
- Casanova, Raul
- Casey, Sean
- Cash, Swin
- Cashman, Brian
- Cason, Aveion
- Casper, Billy
- Cassell, Sam
- Castilla, Vinny
- Castillo, Alberto
- Castillo, Frank
- Castillo, Luis
- Castro, Juan
- Catalanotto, Frank
- Cato, Kelvin
- Ceballos, Cedric
- Cechmanek, Roman
- Cedeno, Ronny
- Centers, Larry
- Cepeda, Orlando
- Cerimele, Mike
- Chacon, Shawn
- Chandler, Chris
- Chandler, Eric
- Chandler, Tyson
- Chang, Michael
- Chapman, Doug
- Chara, Zdeno
- Charles, Bob
- Charleston, Oscar
- Chase, Martin
- Chatman, Antonio
- Chatrier, Philippe
- Chavez, Endy
- Chavez, Eric
- Chavez, Hugo
- Chavous, Corey
- Cheaney, Calbert
- Chelios, Chris
- Chen, Bruce
- Chenowith, Eric
- Chesbro, Jack
- Childers, Matt
- Childs, Chris
- Chimera, Jason
- Ching, Brian
- Choate, Randy
- Chouinard, Marc
- Chrebet, Wayne
- Christian, Bob
- Christiansen, Jason
- Christie, Doug
- Christie, Steve
- Christopher, Nicholas
- Cink, Stewart
- Cirillo, Jeff
- Cisse, Ousmane
- Claiborne, Chris
- Clair, John St.
- Clancy, Kendrick
- Clark, Brady
- Clark, Brett
- Clark, Chris
- Clark, Danny
- Clark, Desmond
- Clark, Earl
- Clark, Jeff
- Clark, Kenny
- Clark, Keon
- Clark, Michael
- Clark, Mike
- Clark, Tony
- Clarkson, John
- Claxton, Speedy
- Clayton, Royce
- Cleaves, Mateen
- Cleeland, Cameron
- Clemens, Kellen
- Clemens, Roger
- Clement, Matt
- Clemons, Charlie
- Clifton, Chad
- Cloud, Mike
- Cloutier, Dan
- Coady, Rich
- Coakley, Dexter
- Cochran, Jack
- Cochrane, Mickey
- Coffey, Kevin
- Cogan, Tony
- Colbert, Jim
- Colbrunn, Greg
- Cole, Chris
- Coleman, Ben
- Coleman, Chris
- Coleman, Derrick
- Coleman, Marco
- Coleman, Marcus
- Coleman, Quincy
- Coleman, Roderick
- Coles, Laveranues
- Collier, Jason
- Collins, Anthony
- Collins, Bobby
- Collins, Dan
- Collins, Doug
- Collins, Eddie
- Collins, Jarron
- Collins, Jason
- Collins, Jimmy
- Collins, Kerry
- Collins, Ryan
- Collins, Tim
- Colome, Jesus
- Colon, Bartolo
- Colvin, Rosevelt
- Combs, Chris
- Combs, Earle
- Comeau, Blake
- Comella, Greg
- Commodore, Mike
- Comrie, Mike
- Conde, Wilman
- Cone, David
- Conine, Jeff
- Conlon, Maria
- Conner, Frank
- Connors, Jimmy
- Conrad, Jimmy
- Conroy, Craig
- Conti, Jason
- Contreras, Jose
- Conway, Brett
- Conway, Curtis
- Conwell, Ernie
- Cook, Brian
- Cook, Damion
- Cook, Dennis
- Cook, John
- Cook, Mike
- Cook, Omar
- Cook, Rashard
- Cooke, Matt
- Coomer, Ron
- Cooper, David
- Copeland, John
- Cora, Alex
- Cordero, Francisco
- Cordova, Marty
- Cormier, Rheal
- Cortez, Jose
- Costa, Fabio
- Cote, Patrick
- Cotts, Neal
- Couch, Tim
- Counsell, Craig
- Couples, Fred
- Courville Jr., Jerry
- Cousin, Terry
- Cowan, Jeff
- Cowan, Patrick
- Cox, Steve
- Crabtree, Tim
- Craft, Jason
- Cramer, Rick
- Crampton, Bruce
- Crawford, Chris
- Crawford, Corey
- Crawford, Jack
- Crawford, Jamal
- Crawford, Richard
- Crede, Joe
- Creek, Doug
- Crenshaw, Ben
- Crisp, Coco
- Crockett, Ray
- Crockett, Zack
- Cronin, Joe
- Cross, Howard
- Crowell, Germane
- Crowley, Mike
- Crumpler, Alge
- Cruz, Jacob
- Cruz, Jose
- Cruz, Nelson
- Csonka, Larry
- Cullen, Matt
- Cullimore, Jassen
- Culpepper, Daunte
- Cummings, Candy
- Cunnane, Will
- Cunningham, Jeff
- Cunningham, Randall
- Cunningham, Richie
- Cunningham, William J.
- Curley, John
- Curry, Dell
- Curry, Eddy
- Curry, JamesOn
- Curry, Michael
- Curtin, Jim
- Curtis, Canute
- Czerkawski, Mariusz