- Vaananen, Ossi
- Vaca, Joselito
- Valderrama, Carlos
- Valentin, Jose
- Valk, Garry
- van Exel, Nick
- Van Gundy, Stan
- van Horn, Keith
- van Ryn, Mike
- Vance, Dazzy
- Vander Wal, John
- Vanderjagt, Mike
- Vanney, Greg
- Varitek, Jason
- Vasher, Nathan
- Vasicek, Josef
- Vasquez, Carlos
- Vaughan, Arky
- Vaughan, Bruce
- Vaughn, Greg
- Vaughn, Jacque
- Vaught, Loy
- Vazquez, Javier
- Veeck, Bill
- Velandia, Jorge
- Venafro, Mike
- Ventura, Robin
- Veres, Dave
- Verplank, Scott
- Vick, Michael
- Vickers, Kipp
- Vidro, Jose
- Vilas, Guillermo
- Villanueva, Charlie
- Villarrial, Chris
- Villone, Ron
- Vina, Fernando
- Vinatieri, Adam
- Vincent, Keydrick
- Vincent, Troy
- Vines, Ellsworth
- Vining, Ken
- Visnovsky, Lubomir
- Vizcaino, Jose
- Vizquel, Omar
- Vogelsong, Ryan
- Vokoun, Tomas
- Volek, Billy
- Voskuhl, Jake
- Vrabel, Mike
- Vujacic, Sasha
- Vyborny, David