In this image taken from video shows projectiles being intercepted...

In this image taken from video shows projectiles being intercepted over Jerusalem, Israel, Tuesday, Oct. 1, 2024. Credit: AP

The Middle East moved closer to a long-feared regional war Wednesday, a day after Iran fired a barrage of missiles at Israel and Israel said it began limited ground incursions into Lebanon targeting the Iran-backed Hezbollah militia.

Israel said it intercepted many of the missiles, and officials in Washington said U.S. destroyers assisted in Israel's defense. Iran said most of its missiles hit their targets. There have been no reports of casualties.

Israeli Prime Minister Benjamin Netanyahu vowed late Tuesday to retaliate against Iran, which he said “made a big mistake tonight and it will pay for it.” An Iranian commander threatened wider strikes on infrastructure if Israel retaliates.

The United Nations Security Council called an emergency meeting for Wednesday to address the spiraling conflict.

Israel and Hezbollah have traded fire across the Lebanon border almost daily since the day after Hamas’ cross-border attack on Oct. 7, 2023, which killed 1,200 Israelis and took 250 others hostage. Israel declared war on the militant group in the Gaza Strip in response. More than 41,000 Palestinians have been killed in the territory, and just over half the dead have been women and children, according to local health officials.

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Updated 36 minutes ago Takeaways from VP debate ... Latest on toxic cleanup at Bethpage park ... Voluntary mastectomies ... Get the latest news and more great videos at NewsdayTV

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