San Diego Padres' Fernando Tatis Jr., right, reacts after having...

San Diego Padres' Fernando Tatis Jr., right, reacts after having a cooler dumped on him by Jake Cronenworth following a walk-off hit against the Detroit Tigers in the tenth inning of a baseball game Wednesday, Sept. 4, 2024, in San Diego. Credit: AP/Derrick Tuskan

SAN DIEGO — Fernando Tatis Jr. hit an RBI single with two outs in the 10th inning to give the San Diego Padres a 6-5 victory over the Detroit Tigers on Wednesday night.

Playing his second game back after being on the injured list since June 22, Tatis singled to left off Jason Foley (3-5) to bring in automatic runner Jackson Merrill, who hit a three-run homer in the fourth and finished a triple shy of the cycle as the Padres overcame a 5-0 deficit.

It was Tatis' first career walkoff hit.

“A very long time,” said Tatis, who reached the majors in 2019 and missed the entire 2022 season due to injuries and a PED suspension. “I'm happy it came here.”

He was sidelined from June 22 until Monday with a stress reaction in his right thighbone.

The Tigers intentionally walked Luis Arraez to get to Tatis.

“I took it personal,” Tatis said. “As soon as I saw four fingers up. But I felt the push I needed, the energy I needed and I just wanted to come through for the boys.”

San Diego Padres' Jackson Merrill, right, celebrates with third base...

San Diego Padres' Jackson Merrill, right, celebrates with third base coach Tim Leiper as he runs the bases after hitting a three-run home run against the Detroit Tigers in the fourth inning of a baseball game Wednesday, Sept. 4, 2024, in San Diego. Credit: AP/Derrick Tuskan

Tatis' jersey was ripped off during a wild celebration near third base. He said half of it broke away during the celebration and he finished it off.

“It just happened. I saw dark and then I had no shirt. It was beautiful. Hopefully it comes more. Just a great moment all the way around," said Tatis, who tossed the jersey into the stands.

Asked about the wisdom of intentionally walking Arraez of Tatis, Merrill said: "I get it, but go ahead, good luck. Walk him to get to Tatis.”

Said manager Mike Shildt: “Oh man, what a big moment. I don't think there was any real doubt he was going to come through. It felt pretty right. Good for him. He had really good at-bats tonight.”

San Diego Padres' Jackson Merrill is congratulated in the dugout...

San Diego Padres' Jackson Merrill is congratulated in the dugout after hitting a three-run home run against the Detroit Tigers in the fourth inning of a baseball game Wednesday, Sept. 4, 2024, in San Diego. Credit: AP/Derrick Tuskan

Jeremiah Estrada (5-2) pitched the 10th for the victory.

Padres right-hander Yu Darvish was activated from the injured list and made his first start since May 29. He allowed three runs and four hits in 2 2/3 innings, struck out four and walked two. During that span, Darvish had been on both the IL, with a left groin strain, and the restricted list due to a family matter.

Darvish left trailing 3-0 after allowing a two-out solo homer to Matt Vierling in the first, his 16th, and one run each in the second and third.

The Tigers went up 5-0 in the fourth when rookie Trey Sweeney hit a two-run home run to deep right off Yuki Matsui, his second.

The Padres started their rally when the lefty-hitting Merrill muscled his three-run shot to left. It was his 22nd homer gave him 82 RBIs, breaking the team rookie record of 79 set by Benito Santiago in 1987.

Merrill has come on strong in the second half and is pushing Pittsburgh's Paul Skenes in the race for NL Rookie of the Year. Merrill was named NL Rookie of the Month for August on Tuesday. The 21-year-old was a prized shortstop prospect but was moved to center field in spring training to replace Trent Grisham, who went to the New York Yankees along with Juan Soto in a blockbuster trade on Dec. 7.

Tatis doubled in the fifth and was on base for Manny Machado's single to left with one out that tied it at 5 and chased starter Keider Montero.

Montero allowed five runs and seven hits, struck out two and walked two.

UP NEXT

Tigers RHP Casey Mize (2-6, 4.25 ERA) and Padres LHP Martín Pérez (4-5, 4.71) are scheduled to start the series finale Thursday night.

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