San Francisco 49ers quarterback Brock Purdy, bottom, runs against Seattle...

San Francisco 49ers quarterback Brock Purdy, bottom, runs against Seattle Seahawks linebacker Boye Mafe (53) during the second half of an NFL football game in Santa Clara, Calif., Sunday, Nov. 17, 2024. Credit: AP/Godofredo A. Vásquez

SANTA CLARA, Calif. — San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing shoulder.

Purdy injured his right shoulder in last Sunday's loss to the Seattle Seahawks. Purdy underwent an MRI that showed no structural damage but the shoulder didn't improve during the week and Purdy was ruled out for the game.

Coach Kyle Shanahan said star defensive end Nick Bosa also will miss the game with injuries to his left hip and oblique. Left tackle Trent Williams is questionable with an ankle injury and will be a game-time decision.

This will be the first time Purdy has missed a start because of an injury since taking over as the 49ers’ quarterback in December 2022. Brandon Allen will start in his place.

The Niners (5-5) are currently in a three-way tie for second in the NFC West, a game behind first-place Arizona, and have little margin for error if they want to get back to the playoffs after making it to the Super Bowl last season.

Purdy has completed 66% of his passes this season for 2,613 yards, 13 TDs, eight interceptions and a 95.9 passer rating that is down significantly from his league-leading mark of 113 in 2023.

Allen has been mostly a backup since being drafted by Jacksonville in 2016. Allen last started a game in Week 18 of the 2021 season for Cincinnati and has thrown just three passes the last three seasons — including none since joining San Francisco in 2023.

San Francisco 49ers quarterback Brock Purdy speaks at a news...

San Francisco 49ers quarterback Brock Purdy speaks at a news conference after an NFL football game against the Seattle Seahawks in Santa Clara, Calif., Sunday, Nov. 17, 2024. Credit: AP/Godofredo A. Vásquez

Joshua Dobbs will be the backup on Sunday.

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