Serena Williams fell to Ajla Tomljanovic, 7-5, 6-7 (4), 6-1, in the third round of the U.S. Open on Friday, Sept. 2, 2022, in what could be her final match.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams his a forehand against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams serves to Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams returns to Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams hits a backhand against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams hits a forehand against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams takes a moment to reset while playing against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams hits a forehand against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Ajla Tomljanovic hits a forehand against Serena Williams during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams returns to Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams hits a short ball against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams reacts against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams reacts to a bad shot while playing Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams reacts against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Ajla Tomljanovic reacts against Serena Williams during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Serena and Venus Williams

Credit: Newsday/J. Conrad Williams Jr.

Serena Williams reacts in the second set against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams returns to Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams reacts against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams returns to Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams reacts during her last game gainst Ajla Tomljanovic at the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams fights her emotions during her last game against Ajla Tomljanovic at the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams waves to fans after she lost her match against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams fights her emotions during her last game against Ajla Tomljanovic at the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams acknowledges fans after she lost her match against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams is interviewed on court after she lost her match against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

Credit: Kathleen Malone-Van Dyke

Serena Williams waves to fans as she leaves the court after she lost her match against Ajla Tomljanovic during the 2022 US Open at the USTA Billie Jean King National Tennis Center on Friday, Sept. 2, 2022.

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